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FITC標記的ASH1蛋白抗體

文字:[大][中][小] 2017-5-2    瀏覽次數:1324    

                              FITC標記的ASH1蛋白抗體                                                                                                                                               
英文名稱Anti-ASH1L/FITC
中文名稱:FITC標記的ASH1蛋白抗體
別    名Absent small and homeotic disks protein 1 homolog; Absent Small or Homeotic Like; ASH 1; ASH 1L; ash1 (absent small or homeotic 1); Ash1 (absent small or homeotic) like; Absent small and homeotic disks protein 1 homolog; ASH1-like protein; ASH-1L; ASH1L_HUMAN; ASH1L1; huASH1; Lysine N-methyltransferase 2H; Probable histone-lysine N-methyltransferase ASH1L.  

詳細介紹:


規格:100ul 
說 明 書100ul  
研究領域細胞生物  神經生物學  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, 
產品應用ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量327kDa
細胞定位細胞膜 
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ASH1L
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation

Function:
Histone methyltransferase. Probably methylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation.

Subcellular Location:
Nucleus. Cell junction, tight junction. Chromosome (Probable). Note=The relevance of tight junction localization is however unclear.

Tissue Specificity:
Widely expressed, with highest level in brain, heart and kidney.

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