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標(biāo)記一抗
英文名稱Anti-APBB1 interacting protein 1/FITC
中文名稱:FITC標(biāo)記的β淀粉樣蛋白前體結(jié)合蛋白B-1抗體
別 名AB1IP; Amyloid beta A4 precursor protein binding family B member 1 interacting protein; Amyloid beta precursor protein binding family B member 1; APBB1 interacting protein 1; OTTHUMP00000019344; PREL 1; PREL1; Proline rich EVH1 ligand 1; Proline rich protein 73; Rap1 GTP interacting adapter molecule; RAP1 interacting adaptor molecule; RARP 1; RARP1; Retinoic acid responsive proline rich protein 1; AB1IP_HUMAN.
規(guī)格:100ul
說 明 書100ul
研究領(lǐng)域腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 結(jié)合蛋白 G蛋白偶聯(lián)受體
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
產(chǎn)品應(yīng)用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量73kDa
細(xì)胞定位細(xì)胞膜
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RIAM/APBB1 interacting protein 1
亞 型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
APBB1IP is a 666 amino acid protein that contains one PH domain, one Ras-associating domain and belongs to the MRL family. Encoded by a gene that maps to human chromosome 10p12.1, APBB1IP likely functions in signal transduction from Ras activation to Actin cytoskeletal remodeling. APBB1IP also suppresses insulin-induced promoter activities, by way of SRE and AP1. The two proline-rich regions of APBB1IP are necessary for AP1 transcription suppression. Ubiquitously expressed, with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes, APBB1IP is induced by all-trans-retinoic acid (ATRA) and mediates Rap 1-induced adhesion. APBB1IP also interacts with RAP 1A, Profilin-1, VASP and Mena
中文名稱:FITC標(biāo)記的β淀粉樣蛋白前體結(jié)合蛋白B-1抗體
別 名AB1IP; Amyloid beta A4 precursor protein binding family B member 1 interacting protein; Amyloid beta precursor protein binding family B member 1; APBB1 interacting protein 1; OTTHUMP00000019344; PREL 1; PREL1; Proline rich EVH1 ligand 1; Proline rich protein 73; Rap1 GTP interacting adapter molecule; RAP1 interacting adaptor molecule; RARP 1; RARP1; Retinoic acid responsive proline rich protein 1; AB1IP_HUMAN.
詳細(xì)介紹：
規(guī)格:100ul
說 明 書100ul
研究領(lǐng)域腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 結(jié)合蛋白 G蛋白偶聯(lián)受體
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
產(chǎn)品應(yīng)用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量73kDa
細(xì)胞定位細(xì)胞膜
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human RIAM/APBB1 interacting protein 1
亞 型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資料：
產(chǎn)品介紹background:
APBB1IP is a 666 amino acid protein that contains one PH domain, one Ras-associating domain and belongs to the MRL family. Encoded by a gene that maps to human chromosome 10p12.1, APBB1IP likely functions in signal transduction from Ras activation to Actin cytoskeletal remodeling. APBB1IP also suppresses insulin-induced promoter activities, by way of SRE and AP1. The two proline-rich regions of APBB1IP are necessary for AP1 transcription suppression. Ubiquitously expressed, with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes, APBB1IP is induced by all-trans-retinoic acid (ATRA) and mediates Rap 1-induced adhesion. APBB1IP also interacts with RAP 1A, Profilin-1, VASP and Mena
